Package: ruv
Title: Detect and Remove Unwanted Variation using Negative Controls
Description: Implements the 'RUV' (Remove Unwanted Variation)
        algorithms.  These algorithms attempt to adjust for systematic
        errors of unknown origin in high-dimensional data.  The
        algorithms were originally developed for use with genomic data,
        especially microarray data, but may be useful with other types
        of high-dimensional data as well.  These algorithms were
        proposed in Gagnon-Bartsch and Speed (2012)
        <doi:10.1093/nar/gkz433>, Gagnon-Bartsch, Jacob and Speed
        (2013), and Molania, et. al. (2019) <doi:10.1093/nar/gkz433>.
        The algorithms require the user to specify a set of negative
        control variables, as described in the references.  The
        algorithms included in this package are 'RUV-2', 'RUV-4',
        'RUV-inv', 'RUV-rinv', 'RUV-I', and RUV-III', along with
        various supporting algorithms.
Version: 0.9.7.2
Date: 2026-08-04
Imports: stats, ggplot2, scales, gridExtra
Suggests: shiny, colourpicker
Authors@R: person(given = "Johann",
                    family = "Gagnon-Bartsch",
                    role = c("aut", "cre"),
                    email = "johanngb@umich.edu")
License: GPL
URL: http://www-personal.umich.edu/~johanngb/ruv/
LazyLoad: yes
NeedsCompilation: yes
Packaged: 2026-10-08 12:24:39 UTC; root
Author: Johann Gagnon-Bartsch [aut, cre]
Maintainer: Johann Gagnon-Bartsch <johanngb@umich.edu>
Repository: https://johanngb.r-universe.dev
Date/Publication: 2026-08-31 23:56:35 UTC
RemoteUrl: https://github.com/cran/ruv
RemoteRef: HEAD
RemoteSha: dea5e535c5896ba6ab8e4c59deccf05b85290759